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Research Compound CatalogRecovery & Regenerative ResearchBPC-157 Research Profile
Recovery & Regenerative Research
Research Use Only

Synthetic Pentadecapeptide — Body Protection Compound Fragment

BPC-157

Pentadecapeptide — Body Protection Compound Fragment

Research StatusLiterature Reviewed Through: July 2026
Research Use Only
Updated Periodically

Research Profiles are reviewed periodically as new peer-reviewed literature becomes available.

Available Strength
5 mg / vial
CAS Number
137525-51-0
Recovery & Regenerative Research laboratory research
Recovery & Regenerative Research
Research at a Glance

Major published findings — summarized in under 30 seconds.

1
Accelerated healing of tendon and ligament tissue has been observed in animal models.
2
Protective effects on gastrointestinal mucosal tissue have been reported across multiple studies.
3
Promotion of new blood vessel formation (angiogenesis) has been observed in tissue repair models.
4
Reductions in inflammatory markers have been documented in both local and systemic administration studies.
5
Protective effects in neural tissue models have been reported, though this area of research is earlier stage.

What Is This Compound?

BPC-157 is a short synthetic peptide that has been studied across a remarkably wide range of tissue types. It was originally derived from a protein found in human gastric juice, and researchers have investigated its effects on tissue repair, inflammation, and recovery across the gastrointestinal tract, tendons, muscles, and the nervous system. One notable characteristic is its stability — unlike most peptides, it remains active in the presence of gastric acid, which has made it useful in both oral and injectable research models. It has one of the broadest published research footprints of any peptide in the regenerative biology category.

Continue below to see what published research has observed so far.

What Has Research Found?

1
Accelerated healing of tendon and ligament tissue has been observed in animal models.
2
Protective effects on gastrointestinal mucosal tissue have been reported across multiple studies.
3
Promotion of new blood vessel formation (angiogenesis) has been observed in tissue repair models.
4
Reductions in inflammatory markers have been documented in both local and systemic administration studies.
5
Protective effects in neural tissue models have been reported, though this area of research is earlier stage.

Want to understand why these findings occur? Continue to the scientific overview below.

The Science Behind It

BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide consisting of 15 amino acids, derived from a partial sequence of human gastric juice protein BPC. It is one of the most extensively studied peptides in regenerative biology research, with a broad literature examining its effects on tissue repair, angiogenesis, and inflammatory signaling across multiple organ systems. BPC-157 is stable in gastric juice and has been studied in both systemic and local administration models.

Mechanism of Action

BPC-157 is proposed to exert its effects through multiple pathways including upregulation of growth hormone receptor expression, modulation of the nitric oxide (NO) system, and promotion of angiogenesis via VEGF and FAK-paxillin signaling. Research suggests it may accelerate fibroblast migration and collagen synthesis, reduce oxidative stress, and modulate the balance between pro- and anti-inflammatory cytokines. Its cytoprotective effects have been studied across gastrointestinal, musculoskeletal, and neural tissue models.

Key Research Characteristics
15-amino acid pentadecapeptide derived from human gastric juice protein BPC
Exceptional aqueous stability — active in gastric juice unlike most research peptides
Studied across the broadest tissue range of any regenerative peptide in published literature
Proposed multi-pathway mechanism including NO system, VEGF angiogenesis, and FAK-paxillin signaling
Investigated in both local and systemic administration models with consistent cytoprotective findings
Extensive preclinical literature spanning gastrointestinal, musculoskeletal, and neural tissue models

Research Applications

Tendon and ligament repair biology
Gastrointestinal mucosal healing research
Angiogenesis and vascular biology studies
Inflammatory signaling modulation
Neural tissue protection and recovery models

Compound Specifications

Available Strength
5 mg / vial
Appearance
White lyophilized powder
Purity
≥98% (HPLC)
Storage Conditions
−20 °C; protect from light
Storage After Reconstitution
4 °C up to 7 days; −80 °C for long-term storage
Molecular Formula
C₆₂H₉₈N₁₆O₂₂
Molecular Weight
1419.5 g/mol
CAS Number
137525-51-0
Research Status
Research Use Only (RUO)

Scientific References

1.Sikiric P, et al. Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications. Curr Neuropharmacol. 2016;14(8):857–865.
2.Chang CH, et al. The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. J Appl Physiol. 2011;110(3):774–780.
3.Sikiric P, et al. Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease. Curr Pharm Des. 2011;17(16):1612–1632.
4.[Placeholder] Peer-reviewed publication on BPC-157 nitric oxide system modulation.
5.[Placeholder] Technical reference: stability profile and reconstitution validation data for BPC-157.

Placeholder entries are reserved for peer-reviewed publications. All references are provided for scientific context only.

Current State of Research

Research Use Only

All information presented on this Research Profile is intended exclusively for laboratory research purposes. This compound is designated Research Use Only (RUO) and is not intended for human consumption, veterinary use, or any clinical application. It is not intended to diagnose, treat, cure, or prevent any disease or medical condition.

This material is sold solely for in vitro research and laboratory investigation by qualified scientific personnel. Kali Research LLC makes no representations regarding the safety or efficacy of this compound for any use outside of controlled laboratory research settings. Researchers are solely responsible for compliance with all applicable laws and institutional regulations governing the use of research compounds.

Not for human consumptionNot for veterinary useNot for clinical applicationQualified researchers onlyIn vitro / laboratory use
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Research Profile
Specifications
Available Strength5 mg / vial
AppearanceWhite lyophilized powder
Purity≥98% (HPLC)
Storage Conditions−20 °C; protect from light
Storage After Reconstitution4 °C up to 7 days; −80 °C for long-term storage
Molecular FormulaC₆₂H₉₈N₁₆O₂₂
Molecular Weight1419.5 g/mol
CAS Number137525-51-0

Need additional technical documentation? Submit an inquiry and our team will respond.

Research Use Only (RUO). Not for human consumption, veterinary use, or clinical application.